Cold Triggers a Hidden Molecular Pathway That Extends Lifespan

16 pointsposted 10 hours ago
by dxs

3 Comments

leereeves

10 hours ago

> It's worth emphasizing that so far these results have only been shown in experiments involving nematodes and human cells

I doubt it would have the same result in a warmblooded animal like humans, because only superficial cells would actually reach the effective temperature.

D-Coder

8 hours ago

From the article:

By genetically boosting CAT–4 levels in the worms' muscles, the team was able to extend their lifespan even at normal or warmer temperatures, suggesting it's possible to reproduce some benefits of the cold without lowering body temperature.

"We were genuinely surprised to find the supplementation significantly extended lifespan, even at standard and warmer temperatures..."