Efficacy of Ibuprofen versus Acetaminophen for Acute Fever in Febrile Children

5 pointsposted 7 hours ago
by XzetaU8
(link.springer.com)

5 Comments

marmarama

6 hours ago

The weaker antipyretic effect of paracetamol/acetaminophen compared with ibuprofen has been known about for decades in adult studies.

It would have been surprising to obtain a different result in children.

pmdulaney

7 hours ago

I had always read that acetaminophen/Tylenol was the gold standard for fever reduction, so this result (ibuprofen/Advil marginally better than acetaminophen/Tylenol) is mildly surprising to me.

srean

6 hours ago

Paracetamol is in general safer than ibuprofen unless you are allergic to paracetamol, in which case the result can be quite gruesome and bloody.

Paracetamol is not a blood thinner. There are not many OTC painkillers that are not blood thinners.

manvillej

7 hours ago

As someone who has been around a sick child, I’ll take the statistically significant temperature reduction at 4h of ibuprofen.

guilhas

3 hours ago

Don't think this is new info

In UK, if you go to the doctor they will recommend acetaminophen/calpol first because ibuprofen anti-inflammatory effect will affect the body's natural response to the "problem" or something like that