which business?? you would need to be more clear? is it a start up? or traditional business? and depends on which sector you work in the advice will change.

             5
    Runway + Σ   cashflow > 0
             y=1

Make a good business.

With so little information, the only advice is "have enough money to run the business and pay salaries even if you get zero income for its first 5 years"