Phage lambda is essentially the "Hello World" of molecular biology. The fact that a "viral micro-manager" like PreS remained hidden in such a heavily sequenced and scrutinized organism is a great reminder of how much "dark matter" there is in the non-coding regions of viral genomes.

We often think of viral infection as a blunt-force destruction of the host, but this shows it's much more of a delicate, timed choreography. Upregulating the host's DnaN via RNA folding rather than just killing the host immediately is a clever survival strategy that we could potentially co-opt for more stable bioreactors.