Polylaminin, a drug considered capable of reversing spinal cord injury

122 pointsposted 14 hours ago
by _aleph2c_
(www1.folha.uol.com.br)

12 Comments

voxleone

13 hours ago

Paper: https://journals.plos.org/plosone/article?id=10.1371/journal...

zipy124

12 hours ago

I think it's actually this one, or perhaps a new one after it:

https://www.medrxiv.org/content/10.1101/2024.02.19.24301010v...

klipklop

9 hours ago

I find this part most interesting: "Three participants (2, 7, 8) regained motor control. i.e., converted to AIS C or D, at the 1-month examination. Other three (4, 5, 6) converted to grade C after 3 months. In the present study we observed that, in contrast to the expected baseline conversion of 15%, 75% (6/8) of the participants regained voluntary motor control after polylaminin treatment. If we consider only those participants that reached discharge, the proportion increases to 100% (6/6)."

giarc

12 hours ago

That paper is an in vitro demonstration whereas the OP article seems to imply they tested on actual patients?

lucasqueiroz

11 hours ago

Yes, it was tested on patients. @ bfdrummond on Instagram was the first one - he is now almost 100% recovered

heavyset_go

8 hours ago

Do we know of other patients?

Sometimes drug and medical device companies will gag patients with non-disparagement agreements, while letting the success stories post freely on social media to promote their product/procedure/etc.

user

12 hours ago

[deleted]

animitronix

13 hours ago

[flagged]

Enginerrrd

11 hours ago

Hey FYI, this isnt the place for that type of comment. This isn't Reddit, and we don't want it to become such.

Unnuanced, potentially inflammatory quips about a vaguely related current political situation just aren't appropriate here.

There are plenty of ways to express the same sentiment without resorting to the type of commentary that is common elsewhere.

I encourage you to read the community guidelines for HN.