Show HN: Synergetica – A Modern, End-to-End Genetic Circuit Design Desktop App

64 pointsposted 5 days ago
by khokao
(github.com)

13 Comments

Archit3ch

5 days ago

Am I the only one who expected Electrical Circuits designed via Genetic Algorithms?

bythreads

5 days ago

Same

bythreads

5 days ago

Didn't realize circuit was used that way in genome / dna stuff

khokao

5 days ago

Thanks for checking this out! In this context, “genetic circuit” refers to synthetic biology constructs that use biological components (such as promoters and proteins) to regulate gene expression, rather than electrical circuits created by genetic algorithms.

the__alchemist

3 days ago

> To get started, install both the backend Docker image and the desktop application.

> If the Docker engine is running when you open the desktop app, the Docker container will automatically start and the API will launch on port 7007.

There is no reasonable reason for this, given the context of a PC application. I also write moecular-bio PC applications, and this has not been a consideration.

Centigonal

5 days ago

Could someone please explain what a genetic circuit is, for those out of the loop (like me)?

bglazer

5 days ago

Protein A binds to DNA at a specific spot near Gene B and allows the cell to make more Protein B (which is the product of Gene B). Protein B then binds near Gene A and prevents Protein A from being produced. This causes oscillations as the genes A and B activate and repress each other. The details are quite a bit more complex, but that's the basic idea. You can get very complex circuits that implement very interesting and useful behavior. Imagine engineering an immune cell so that it only attacks cancer cells displaying certain proteins on it. More generally, an insanely complex web of interactions between genes and proteins and other chemicals governs the development of all multicellular organisms.

Centigonal

5 days ago

That's very interesting. Thank you!

khokao

5 days ago

Thank you so much for the clear explanation!

sirjaz

5 days ago

What was the decision to use typescript? It looks like another electron app

GlacierFox

5 days ago

What specifically makes apps look like they've been built using electron?

goku12

5 days ago

Looks like it's made with Tauri and React, rather than Electron.